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Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes

✍ Scribed by Sandrine A. Tinton; Pedro M. Buc-Calderon


Book ID
117110513
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
400 KB
Volume
446
Category
Article
ISSN
0014-5793

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Increased phosphorylation of the translational repressor protein 4E-BP1 was found in the cell line derived from the tumor induced in Syrian hamster by Rous sarcoma virus (RSV). This was accompanied by its dissociation from the complex with initiation factor eIF4E. The ribosomal S6 protein kinase p70