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Importance of B cell co-stimulation in CD4+ T cell differentiation: X-linked agammaglobulinaemia, a human model

✍ Scribed by H. Martini; V. Enright; M. Perro; S. Workman; J. Birmelin; E. Giorda; I. Quinti; V. Lougaris; M. Baronio; K. Warnatz; B. Grimbacher


Book ID
108701397
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
284 KB
Volume
164
Category
Article
ISSN
0009-9104

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Nonpolymorphic interactions between the T cell differentiation antigens CD4 or CD8 and major histocompatibility complex (MHC)-encoded molecules have been postulated to participate in antigen recognition of MHC-restricted T cells. This would imply simultaneous binding of CD418 and of the T cell recep