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Implication of the circadian system in the modulation of the intracellular load of oxidized protein and its removal by the proteasome

✍ Scribed by Desvergne, A.; Ugarte, N.; Petropoulos, I.; Friguet, B.


Book ID
122073861
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
58 KB
Volume
65
Category
Article
ISSN
0891-5849

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## Abstract The generation of free radicals and the resulting oxidative modification of cell structures are omnipresent in mammalian cells. This includes the permanent oxidation of proteins leading to the disruption of the protein structure and an impaired functionality. In consequence, these oxidi