Implication of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) for Neuroprotection of Nicotinic Acetylcholine Receptor Signaling in PC12 Cells
✍ Scribed by Aiko Tominaga; Hideki Sugawara; Kazuhiko Inoue; Atsuro Miyata
- Book ID
- 107575100
- Publisher
- Humana Press Inc
- Year
- 2008
- Tongue
- English
- Weight
- 184 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0895-8696
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Pituitary adenylate cyclase activating polypeptide (PACAP) was isolated from ovine hypothalamus and known to stimulate the production of cAMP in anterior pituitary cells. In the recent report, the expression of PACAP was detected in preovulatory follicles, and treatment with PACAP stimulated the pro
## Abstract Parkinson's disease (PD) and 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) toxicity are both associated with dopaminergic neuron death in the substantia nigra. Although a variety of evidence has shown that degenerative cells have apoptotic features, the role of apoptosis in diseas
## Abstract Pituitary adenylate cyclase‐activating polypeptide (PACAP), a neurotrophic and neuromodulatory peptide, was recently shown to enhance NMDA receptor‐mediated currents in the hippocampus (Macdonald, et al. 2005. J Neurosci 25:11374–11384). To check if PACAP might also modulate AMPA recept