The pharmacokinetics of pafenolol, a highly selective /?,-adrenoceptor antagonist, have been studied in starved and unstarved rats. Separate groups received intravenous doses (0.3 and 3.0pmol kg-I) and oral doses (1 and 25pmol kg-I). The systemic clearance of pafenolol was constant in the dose range
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies
✍ Scribed by Radojka M. Savic; Daniël M. Jonker; Thomas Kerbusch; Mats O. Karlsson
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 305 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1573-8744
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