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Impairments of long-term potentiation in hippocampal slices of β-amyloid-infused rats

✍ Scribed by Akio Itoh; Tadashi Akaike; Masahiro Sokabe; Atsumi Nitta; Ryuichi Iida; Ana Olariu; Kiyofumi Yamada; Toshitaka Nabeshima


Book ID
114017528
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
234 KB
Volume
382
Category
Article
ISSN
0014-2999

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Although it is generally believed that amyloid ␤ (A␤) peptides contribute to the pathogenesis of Alzheimer's disease, the precise role of these peptides in the development of memory loss of Alzheimer's disease, has not been fully understood. The present study examined the effect of several synthetic