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Impairment of the exercise-induced increase in muscle perfusion in McArdle's disease

✍ Scribed by Philippe Jehenson; Anne Leroy-Willig; Eric Kerviler; Pascal Merlet; Denis Duboc; André Syrota

Book ID
104946822
Publisher
Springer
Year
1995
Tongue
English
Weight
509 KB
Volume
22
Category
Article
ISSN
0340-6997

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Impairment of muscle mitochondrial oxidative metabolism in McArdle's disease
✍ Nicola De Stefano; Zohar Argov; Paul M. Matthews; George Karpati; Douglas L. Arn 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 535 KB

Impairment of muscle glycogenolysis in McArdle's disease (myophosphorylase deficiency) leads to exercise intolerance and exercise-induced myalgia. The pathophysiology of these symptoms is not entirely clear. We used phosphorus magnetic resonance spectroscopy to measure muscle phosphate metabolite co