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Impairment of Drug Biotransformation in Renal Disease: An In Vitro Model

✍ Scribed by Taburet, A.M.; Vincent, I.; Perello, L.; Coret, B.; Baune, B.; Furlan, V.


Book ID
110019814
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
157 KB
Volume
59
Category
Article
ISSN
0009-9236

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The kinetics of drug transfer from a buffered aqueous phase (compartment A) through a lipid phase (compartment B ) to another aqueous buffered phase (compartment C) are reported. These kinetics are obtained from an in vifm model system which in important respects mimics drug transfer during the abso