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Impaired renal function in a patient with diuretic abuse

✍ Scribed by G. Yasuda; T. Takizawa; K. Shibata; N. Hirawa; M. Kihara; Y. Toya; H. Shionoiri; S. Umemura


Book ID
106288826
Publisher
Springer
Year
2002
Tongue
English
Weight
123 KB
Volume
6
Category
Article
ISSN
1342-1751

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Metabolism of the diuretic bumetanide in
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The pharmacokinetics and metabolism of orally administered bumetanide were studied in five healthy subjects and in five patients with renal insufficiency. Healthy subjects excreted 51% of the dose as unchanged drug in the urine, whilst the patients with renal insufficiency excreted only 11% of the d