Using a sister chromatid differentiation technique, cell cycle study of stimulated lymphocytes of B-Cell chronic lymphocytic leukemia (B-CLL) revealed their cell cycle progression to be similar to that of normal lymphocytes stimulated by T-cell and various polyclonal B-cell activators (PBA). The chr
Impaired recirculation of b lymphocytes in chronic lymphocytic leukemia
β Scribed by H. D. Flad; C. Huber; K. Bremer; H. D. Menne; H. Huber
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 580 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0014-2980
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B cell and T cell characteristics of circulating lymphocytes were studied in 13 patients with chronic lymphocytic leukemia (C.L.L.). Immunofluorescence of surface immunoglobulins and rosette formation using sensitized sheep red blood cells were employed to detect B cells. Rosette formation with untr
## Abstract BβCLL is the most common adult leukemia in the Western world. It is a neoplasia of mature looking Bβmonoclonal lymphocytes coβexpressing the CD5 antigen (involving the blood, the bone marrow, the lymph nodes and related organs). Much new information about the nature of the neoplastic ce