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Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

✍ Scribed by Baiyang Sheng; Xinglong Wang; Bo Su; Hyoung-gon Lee; Gemma Casadesus; George Perry; Xiongwei Zhu

Book ID
111184768
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
543 KB
Volume
120
Category
Article
ISSN
0022-3042

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## Abstract Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to t