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Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia

โœ Scribed by Sathyasaikumar, K. V.; Stachowski, E. K.; Wonodi, I.; Roberts, R. C.; Rassoulpour, A.; McMahon, R. P.; Schwarcz, R.


Book ID
118734003
Publisher
Oxford University Press
Year
2010
Tongue
English
Weight
164 KB
Volume
37
Category
Article
ISSN
0586-7614

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Expression of the kynurenine pathway enz
โœ Christine L Miller; Ida C Llenos; Jeanette R Dulay; Meliza M Barillo; Robert H Y ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 683 KB

Markers of the kynurenine pathway were studied in postmortem frontal cortex obtained from individuals with schizophrenia and controls. Quantitative endpoint RT-PCR was used to measure mRNA transcripts. Of the two enzymes capable of catalyzing the first step in the pathway, tryptophan 2,3-dioxygenase