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Impaired insulin secretion of aging: Role of renal failure and hyperparathyroidism

✍ Scribed by Massry, Shaul G; Fadda, George Z; Zhou, Xin-Jin; Chandrasoma, Parakrama; Cheng, Linda; Filburn, Charles R

Book ID
109881858
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
602 KB
Volume
40
Category
Article
ISSN
0085-2538

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The role of ion channels in insulin secr
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## Abstract Ion channels in beta cells regulate electrical and secretory activity in response to metabolic, pharmacologic, or neural signals by controlling the permeability to K^+^ and Ca^2+^. The ATP‐sensitive K^+^ channels act as a switch that responds to fuel secretagogues or sulfonylureas to in