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Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57

✍ Scribed by Garbi, Natalio; Tanaka, Satoshi; Momburg, Frank; Hämmerling, Günter J


Book ID
109923196
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
424 KB
Volume
7
Category
Article
ISSN
1529-2908

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## Abstract The identification of endogenously produced antigenic peptides presented by MHC class I molecules has opened the way to peptide‐based strategies for CTL induction __in vivo__. Here we demonstrate that the induction __in vivo__ of CTL directed against naturally processed antigens can be