Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expression
β Scribed by He Wang; Bronia Olszewski; Wendy Rosebury; Dongkai Wang; Andrew Robertson; Joan A Keiser
- Book ID
- 116287939
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 221 KB
- Volume
- 315
- Category
- Article
- ISSN
- 0006-291X
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Secreted protein, acidic and rich in cysteine (SPARC), is a multifunctional matricellular glycoprotein. In vitro, SPARC has antiangiogenic properties, including the ability to inhibit the proliferation and migration of endothelial cells stimulated by bFGF and VEGF. Previously, we demonstrated that p