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Impact of TEL/AML1-positive patients on age distribution of childhood acute lymphoblastic leukemia in Czech Republic

✍ Scribed by Trka, J; Zuna, J; Hrušák, O; Kalinová, M; Mužíková, ; Lauschman, H; Starý, J


Book ID
110053875
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
278 KB
Volume
12
Category
Article
ISSN
0887-6924

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Prenatal origin of TEL-AML1–positive acu
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Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer. The peak incidence of ALL between ages 2 and 5 is accounted for by one subtype, referred to as common acute lymphoblastic leukemia (cALL). About 25% of cALL patients have the TEL-AML1 gene fusion derived from the t(12;21