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Impact of Protein Denaturants and Stabilizers on Water Structure

✍ Scribed by Batchelor, Joseph D.; Olteanu, Alina; Tripathy, Ashutosh; Pielak, Gary J.


Book ID
120570806
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
125 KB
Volume
126
Category
Article
ISSN
0002-7863

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## Abstract Virtually all studies of the protein‐folding reaction add either heat, acid, or a chemical denaturant to an aqueous protein solution in order to perturb the protein structure. When chemical denaturants are used, very high concentrations are usually necessary to observe any change in pro