✦ LIBER ✦

Impact of neck dissection on long-term feeding tube dependence in patients with head and neck cancer treated with primary radiation or chemoradiation

✍ Scribed by Miriam N. Lango; Brian Egleston; Kevin Ende; Steven Feigenberg; David J. D'Ambrosio; Roger B. Cohen; Sidrah Ahmad; Nicos Nicolaou; John A. Ridge

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 88 KB
Volume: 32
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.21188

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background.

The impact of posttreatment neck dissection on prolonged feeding tube dependence in patients with head and neck squamous cell cancer (HNSCC) treated with primary radiation or chemoradiation remains unknown.

Methods.

We conducted a retrospective cohort study using propensity score adjustment to investigate the effect of neck dissection on prolonged feeding tube dependence.

Results.

A review of 67 patients with node‐positive HNSCC (T1‐4N1‐3), treated with primary radiation or chemoradiation, with no evidence of tumor recurrence and follow‐up of at least 24 months, was performed. Following adjustment for covariates, the relative risk (RR) of feeding tube dependence at 18 months was significantly increased in patients treated with posttreatment neck dissection (RR 4.74, 95% confidence interval [CI] 2.07‐10.89). At 24 months, the relative risk of feeding tube dependence in the patients having undergone neck dissection increased further (RR 7.66, 95% CI 2.07‐10.89). Of patients with feeding tubes 2 years after completing treatment, 75% remained feeding tube dependent.

Conclusion

📜 SIMILAR VOLUMES

Prospective study of percutaneous endosc

Prospective study of percutaneous endoscopic gastrostomy tubes versus nasogastric tubes for enteral feeding in patients with head and neck cancer undergoing (chemo)radiation

✍ June Corry; Wendy Poon; Narelle McPhee; Alvin D. Milner; Deborah Cruickshank; Sa 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB 👁 1 views

## Abstract ## Background Percutaneous endoscopic gastrostomy (PEG) tubes have largely replaced nasogastric tubes (NGTs) for nutritional support of patients with head and neck cancer undergoing curative (chemo) radiotherapy without any good scientific basis. ## Methods A prospective study was co

Impact of early percutaneous endoscopic

Impact of early percutaneous endoscopic gastrostomy tube placement on nutritional status and hospitalization in patients with head and neck cancer receiving definitive chemoradiation therapy

✍ Charles E. Rutter; Susannah Yovino; Rodney Taylor; Jeffrey Wolf; Kevin J. Cullen 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB 👁 2 views

Background. This study analyzed the impact of timing of percutaneous endoscopic gastrostomy (PEG) tube placement on clinical endpoints in patients undergoing concurrent chemoradiation therapy (CRT). Methods. In all, 111 patients who underwent CRT for locally advanced squamous cell carcinoma of the

Radiation-induced Xerostomia in patients

Radiation-induced Xerostomia in patients with head and neck cancer: Pathogenesis, impact on quality of life, and management

✍ Mark S. Chambers; Adam S. Garden; Merrill S. Kies; Jack W. Martin 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 2 views

## Abstract ## Background. Xerostomia is a common, debilitating complication of radiation therapy (RT) for head and neck cancer. This article reviews the pathogenesis of radiation‐induced xerostomia, its impact on quality of life (QOL), and treatment options. ## Methods. Virtually all patients u

Patients with head and neck cancer cured

Patients with head and neck cancer cured by radiation therapy: A survey of the dry mouth syndrome in long-term survivors

✍ Oda B. Wijers; Peter C. Levendag; Mirjam M. J. Braaksma; Meindert Boonzaaijer; L 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB 👁 1 views

## Abstract ## Background Xerostomia can have a significant impact on the quality of life of patients treated by radiation therapy (RT) for cancer in the head and neck. The first aim of the study was to evaluate the degree of xerostomia in 39 long‐term survivors treated between 1965–1995 by conven

Patient-reported measurements of oral mu

Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy : Demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life

✍ Linda S. Elting; Dorothy M. Keefe; Stephen T. Sonis; Adam S. Garden; F. K. L. Sp 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB 👁 2 views

## Abstract ## BACKGROUND. The risk, severity, and patient‐reported outcomes of radiation‐induced mucositis among head and neck cancer patients were prospectively estimated. ## METHODS. A validated, patient‐reported questionnaire (OMDQ), the FACT quality of life (QOL), and the Functional Assessm

Impact of nutrition support on treatment

Impact of nutrition support on treatment outcome in patients with locally advanced head and neck squamous cell cancer treated with definitive radiotherapy: A secondary analysis of RTOG trial 90-03

✍ Rachel Rabinovitch; Barbara Grant; Brian A. Berkey; David Raben; Kie Kian Ang; K 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 1 views

## Background: The aim was to evaluate the relationship between nutrition support (ns) on host toxicity and cancer outcome in patients with locally advanced head and neck squamous cell carcinoma (hnscc) undergoing definitive radiotherapy (xrt). ## Methods: We performed a secondary analysis of rad