Background. This study analyzed the impact of timing of percutaneous endoscopic gastrostomy (PEG) tube placement on clinical endpoints in patients undergoing concurrent chemoradiation therapy (CRT). Methods. In all, 111 patients who underwent CRT for locally advanced squamous cell carcinoma of the
Prospective study of percutaneous endoscopic gastrostomy tubes versus nasogastric tubes for enteral feeding in patients with head and neck cancer undergoing (chemo)radiation
✍ Scribed by June Corry; Wendy Poon; Narelle McPhee; Alvin D. Milner; Deborah Cruickshank; Sandro V. Porceddu; Danny Rischin; Lester J. Peters
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 121 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background
Percutaneous endoscopic gastrostomy (PEG) tubes have largely replaced nasogastric tubes (NGTs) for nutritional support of patients with head and neck cancer undergoing curative (chemo) radiotherapy without any good scientific basis.
Methods
A prospective study was conducted to compare PEG tubes and NGTs in terms of nutritional outcomes, complications, patient satisfaction, and cost.
Results
There were 32 PEG and 73 NGT patients. PEG patients sustained significantly less weight loss at 6 weeks post‐treatment (median 0.8 kg gain vs 3.7 kg loss, p < .001), but had a high insertion site infection rate (41%), longer median duration of use (146 vs 57 days, p < .001), and more grade 3 dysphagia in disease‐free survivors at 6 months (25% vs 8%, p = .07). Patient self‐assessed general physical condition and overall quality of life scores were similar in both groups. Overall costs were significantly higher for PEG patients.
Conclusion
PEG tube use should be selective, not routine, in this patient population. © 2009 Wiley Periodicals, Inc. Head Neck, 2009
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