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Impact of genetic background on spontaneous or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumorigenesis in Min/+ mice

✍ Scribed by Inger-Lise Steffensen; Jan Alexander


Book ID
116333979
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
131 KB
Volume
240
Category
Article
ISSN
0304-3835

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## Abstract 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__]pyridine (PhIP) is the most abundant heterocyclic amine derived from food, possibly involved in human carcinogenesis. We evaluated the formation of PhIP‐DNA adducts in lymphocytes from 76 incident colorectal cancer patients likely to be exposed