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Immunotherapy of Rheumatoid Arthritis Targeting Inflammatory Cytokines and Autoreactive T Cells

✍ Scribed by Guangjie Chen


Publisher
Springer
Year
2010
Tongue
English
Weight
248 KB
Volume
58
Category
Article
ISSN
0004-069X

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Clonally expanded VΞ±12+ (AV12S1),CD8+ T
✍ Samuel M. Behar; Chris Roy; James Lederer; Pat Fraser; Michael B. Brenner πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 889 KB

Objective. Previously, we showed that 15-20% of patients with rheumatoid arthritis (RA) have oligoclonal expansions of peripheral blood CDS+ T cells expressing T cell receptors encoded by the VJ2 (AV12S1) gene. To better understand the significance of these expansions, the present study was undertak