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Immunosuppressive mechanism for human B cell activation by FK506

โœ Scribed by N. Suzuki; T. Sakane; Y. Murakawa; Y. Ueda; T. Tsuchida; T. Tsunematsu


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
71 KB
Volume
10
Category
Article
ISSN
0192-0561

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## Abstract The effects of the immunosuppressants cyclosporin A (CsA), FK506 and rapamycin have been compared using murine B cells activated with a variety of mitogens. FK506 is a macrolide antibiotic that has been recently shown to inhibit T cell activation by a mechanism that appears similar to t