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Immunosuppressive Effects and Mechanisms of Leflunomide in Dengue Virus Infection of Human Dendritic Cells

โœ Scribed by Wan-Lin Wu; Ling-Jun Ho; Pei-Chih Chen; Yi-Ting Tsai; Seng-Ting Hsu; Deh-Ming Chang; Jenn-Haung Lai

Book ID
106406168
Publisher
Springer
Year
2011
Tongue
English
Weight
678 KB
Volume
31
Category
Article
ISSN
0271-9142

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## Abstract Dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) are severe complications of dengue virus (DV) infection. However, the pathogenesis of hemorrhage induced by dengue virus infection is poorly understood. Since endothelial cells play a pivotal role in the regulation of hemostas