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Immunophenotype of mitotic cells with clonal chromosome abnormalities demonstrating multilineage involvement in acute myeloid leukemia

✍ Scribed by Stefan Suciu; Wolfgang Zeller; Hans J. Weh; Dieter K. Hossfeld


Book ID
119105854
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
666 KB
Volume
70
Category
Article
ISSN
0165-4608

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Clonal abnormalities of chromosome(s) 7 were investigated in two patients with acute lymphoblastic leukemia. The abnormal karyotypes were 46,XY.-7,de1(6)(qI 3qZl),+i(7q)/47,XY,deI(6),+i(7q) in case I, and 46,XX.-7,t(4;1 l)(qZl;q23), + i(7q) in case 2. DNA from leukemic tissue was investigated with S