Immunopharmacology of tumor necrosis factors α and β
✍ Scribed by Michael A. Palladino Jr; Bryan S. Finkle
- Book ID
- 119111857
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 234 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0165-6147
No coin nor oath required. For personal study only.
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Distinctions between tumor necrosis factor, TNF-alpha, and lymphotoxin, TNF-beta, have previously been based on the differences between their protein sequences, biological activity, and molecular regulation. In the past year, elucidation of the molecular nature of the two molecules and the interacti
Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor a (TNFa). Seven of 12 sera from RA patients contained TNFa, while only 1 of those from reactive arthritis patients was positive.