## Abstract Very high levels of placental‐like alkaline phosphatases (PLAP‐like enzymes) were observed in tissues from 13 typical seminomas. Four tumors with seminoma components contained these enzymes to varying degrees, and other testicular tumors had them in smaller or non‐detectable amounts. An
Immunoperoxidase study of alkaline phosphatase in testicular tumor
✍ Scribed by Toshikazu Uchida; Toshihiko Shimoda; Hisahiro Miyata; Toshio Shikata; Shiro Iino; Hiroshi Suzuki; Toshitsugu Oda; Kazuyuki Hirano; Mamoru Sugiura
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 974 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Indirect immunofluorescence and radioimmuno‐assay with specific rabbit antisera demonstrated the occurrence of alphafetoprotein (AFP), carcino‐embryonic antigen (CEA) and placental alkaline phosphatase (PLAP) in primary testicular tumor cells. Embryonal carcinomas had AFP‐ and CEA‐conta
In humans, alkaline phosphatases are encoded by one tissue-non-specific alkaline phosphatase (TNAP) gene and three tissue-specific alkaline phosphatase genes, intestinal, placental (PLAP), and germ cell-specific alkaline phosphatase (GCAP). Although the presence of alkaline phosphatases in testicula