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Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis

✍ Scribed by Ian R van Driel; Alan G Baxter; Karen L Laurie; Tricia D Zwar; Nicole L La Gruta; Louise M Judd; Katrina L Scarff; Pablo A Silveira; Paul A Gleeson


Book ID
117799130
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
581 KB
Volume
1
Category
Article
ISSN
1568-9972

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## Abstract Human autoimmune gastritis (AIG) is an organ‐specific inflammatory disorder leading to gastric atrophy and pernicious anemia. Gastric H^+^,K^+^‐ATPase was identified as the autoantigen in both human disease and experimental murine AIG (EAIG). Studies of EAIG significantly contributed to