Immunomagnetic detection of micrometastatic cells in bone marrow predicts survival of patients with malignant melanoma and osteosarcoma
✍ Scribed by Ø. Fodstad; H.K. Høifødt; S. Faye; Ø. Bruland; L. Holstad; S. Aamdal
- Book ID
- 117657971
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 186 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0959-8049
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To determine the incidence and clinical signifance of micrometastases in the bone marrow of breast carcinoma patients, we performed an immunoalkaline phosphatase assay using anticytokeratin (AEI , AE3, MAK-6) and antiepithelial (1 13F1, 260F9, 3 17G5) antibodies on the bone marrow aspirates of 71 st
## Abstract ## BACKGROUND The efficient detection and characterization of micrometastatic cells in the bone marrow of patients with breast carcinoma are of prognostic and therapeutic importance. The technique used must overcome the challenges that result from the small number of target cells (1 pe