The association between maternal diabetes mellitus and congenital defects has been well documented. However, few data exist on the potential teratogenic effect of gestational diabetes (GD). We analyzed 19,577 consecutive infants with malformations of unknown cause and compared the offspring of mothe
Immunology in diabetic pregnancy: activated T cells in diabetic mothers and neonates
β Scribed by U. Di Mario; F. Dotta; P. Gargiulo; J. Sutherland; D. Andreani; K. Guy; A. Pachi; F. Fallucca
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 628 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0012-186X
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## Background: Diabetes in pregnancy has been reported to cause congenital malformations in the offspring. hyperglycemia-induced teratogenicity is related to the increased oxidative stress and depletion of glutathione (gsh) in fetal tissues. ## Methods: In the present study, we have examined the
## Objective: Our purpose was to investigate the relationship between the birth weights and 24-h urinary c-peptide in infants of diabetic mothers. ## Methods: Sixty pregnancies with gestational diabetes mellitus (dm) were enrolled. neonatal urine was collected for the first and second 24 h for me