Immunological response of nasopharyngeal carcinoma patients to the Epstein-Barr-virus-coded thymidine kinase expressed in Escherichia coli
✍ Scribed by Edward Littler; William Newman; John R. Arrand
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 586 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0020-7136
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## Abstract Epstein‐Barr virus (EBV) encoded DNA polymerase (POL) was cloned and over‐expressed in __Escherichia coli__. Western blot analysis confirmed the presence of antibody to this POL protein in sera from nasopharyngeal carcinoma (NPC) patients. By Western blot analysis, moderate to high conc
## Abstract We have examined serial sera from 17 juvenile patients with nasopharyngeal carcinoma (NPC) for their capacity to neutralize the activity of Epstein‐Barr virus (EBV)‐specific DNase. The results revealed that NPC patients who became long‐term survivors (LTS) without evidence of the diseas