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Immunological function of thymoma and pathogenesis of paraneoplastic myasthenia gravis

✍ Scribed by Meinoshin Okumura; Yoshitaka Fujii; Hiroyuki Shiono; Masayoshi Inoue; Masato Minami; Tomoki Utsumi; Yoshihisa Kadota; Yoshiki Sawa

Book ID
107497452
Publisher
Springer Japan
Year
2008
Tongue
Japanese
Weight
452 KB
Volume
56
Category
Article
ISSN
1863-6705

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Myasthenia gravis (MG) and its animal model experimental autoimmune myasthenia gravis (EAMG) are caused by autoantibodies against nicotinic acetylcholine receptor (AChR) in skeletal muscle. The production of anti-AChR antibodies is mediated by cytokines produced by CD4+ and CD8+ T helper (Th) cells.