Immunological consequences of cross-species infection of porcine endothelial cells with human cytomegalovirus
β Scribed by A. L. Millard; M. Ghielmetti; M. K. J. Schneider; N. J. Mueller; J. D. Seebach
- Book ID
- 110905099
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 71 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0908-665X
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Human cytomegalovirus (CMV) has been associated with vascular pathology. In vivo, CMV is present in vessel wall cells during acute and chronic infections as well as in atherosclerotic lesions. CMV nucleic acids and proteins have also been detected within Kaposi's sarcoma lesions. Because of these as
## Abstract Human cytomegalovirus (CMV), known to replicate in vitro in human fibroblastic cells, was found to replicate in epithelial human amnion (HA) cells. Large syncytia formed in these cells after infection with CMV; inclusion bodies were observed in the nuclei, and CMV antigens were demonstr