Cytogenetic and molecular studies have suggested that the 3p14.2 chromosome subband contains tumor suppressor genes involved in the pathogenesis of many types of human cancers. Recently, the FHIT (fragile histidine triad) gene was identified in this part of chromosome 3 as a candidate suppressor gen
Immunologic studies of normal, benign, and malignant human prostatic tissue
β Scribed by R. J. Ablin
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- English
- Weight
- 481 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Specific endothelin-1 (ET1) binding sites have been demonstrated in membranes derived from normal (NP) and benign hyperplasic (BPH) human prostate using an lZ5I-ETl binding assay. '=I saturation experiments and Scatchard analysis demonstrated the existence of a homogeneous population of binding site
Telomerase is a ribonucleoprotein that synthesizes telomeric DNA on chromosomal ends. While telomerase is undetectable in most normal somatic tissues, telomerase activation has been detected by a polymerase chain reaction (PCR)-based assay (TRAP) in many immortal cell lines and various cancers, incl
BACKGROUND. Prostate trophism depends on DHT formed from T by the enzyme 5β£-R. Two 5β£-R isoforms with different biochemical characteristics have been cloned. Also estrogens might contribute to the prostate growth; however, their intraglandular formation by the enzyme aromatase is still debated. The
## BACKGROUND. A variety of hormones have demonstrated effects on prostatic tissue growth dynamics. Our goal was to define the effect of dihydrotestosterone (DHT), epidermal growth factor (EGF), and prolactin (PRL) on prostate cellular proliferation. METHODS. Thirty benign human prostatic hyperpla