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Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue

✍ Scribed by Alfred Hobisch; Hermann Rogatsch; Anton Hittmair; Dietmar Fuchs; Georg Bartsch Jr; Helmut Klocker; Georg Bartsch; Zoran Culig

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 285 KB
Volume: 191
Category: Article
ISSN: 0022-3417
DOI: 10.1002/1096-9896(2000)9999:9999<::aid-path633>3.0.co;2-x

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✍ Willman, Joseph H.; Holden, Joseph A. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 455 KB 👁 2 views

## BACKGROUND. The DNA topoisomerase II-alpha (topo II-alpha)-targeting drug etoposide was recently shown to be an active agent in the combined chemotherapy of hormoneinsensitive prostatic carcinoma. Aside from being the molecular target of etoposide, topo II-alpha is also a cell proliferation mark