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Immunohistologically definable light chain restriction in autoimmune disease

✍ Scribed by K. Michael Pollard; Voula Toumasatos; Louise Furphy; John Webb


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
288 KB
Volume
156
Category
Article
ISSN
0022-3417

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Analysis of serum immunoglobulins from patients suffering from autoimmune disease has shown that pathogenically relevant autoantibodies directed at organ specific antigens are light chain restricted, i.e., they are entirely lambda or kappa type in a given patient. Furthermore, plasma cells involved

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