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Immunohistologically definable light chain restriction in autoimmune disease: Author's reply

โœ Scribed by B. Jasani


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
167 KB
Volume
156
Category
Article
ISSN
0022-3417

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Immunohistologically definable light cha
โœ Dr Bharat Jasani ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 707 KB

Analysis of serum immunoglobulins from patients suffering from autoimmune disease has shown that pathogenically relevant autoantibodies directed at organ specific antigens are light chain restricted, i.e., they are entirely lambda or kappa type in a given patient. Furthermore, plasma cells involved