Objective. To investigate the production of type I1 collagen (CII) antibodies in the synovial fluid (SF) of rheumatoid arthritis (RA) patients, and to examine the HLA dependence of this local production. Methods. The ELISPOT method was used for enumerating anti-CII-reactive cells. Serologic tissue
Immunohistologic demonstration of type ii collagen in synovial fluid phagocytes of osteoarthritis and rheumatoid arthritis patients
โ Scribed by Larry W. Moreland; Tod Stewart; Renate E. Gay; Guo Qiang Huang; Nancy McGee; Steffen Gay
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 695 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0004-3591
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๐ SIMILAR VOLUMES
Production of antibodies to IgG and to type I and type I1 collagen (CI and CII) was analyzed by enzymelinked immunospot assay in patients with rheumatoid arthritis (RA) and patients with other inflammatory or degenerative joint diseases. Anti-CII-secreting cells, generally in high numbers, were foun
## Abstract ## Objective To find evidence for the presence of endothelial precursor cells, which can induce new vessel formation, in the synovial tissue of patients with rheumatoid arthritis (RA) and osteoarthritis (OA). ## Methods Precursor cells in the synovial tissue of 18 RA patients and 15