Microsatellite instability in multiple c
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Monica Pedroni; Maria Grazia Tamassia; Antonio Percesepe; Luca Roncucci; Piero B
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Article
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1999
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John Wiley and Sons
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French
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Tumor multiplicity is a hallmark of hereditary cancers: in the colon-rectum multiple tumors represent 5-10% of all colorectal cancer cases. A portion of these cases belongs to hereditary non-polyposis colorectal cancer (HNPCC), a genetic cancer syndrome due to mismatch repair (MMR) gene mutations, p