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Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum

✍ Scribed by Elin Lehrmann; Antonio Molinari; Carmela Speciale; Robert Schwarcz

Book ID: 105911649
Publisher: Springer-Verlag
Year: 2001
Tongue: English
Weight: 436 KB
Volume: 141
Category: Article
ISSN: 0014-4819
DOI: 10.1007/s002210100887

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## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by “norm