Programmed cell death 1 (PD-1) and its l
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Liqing Wang; Rongxiang Han; WayneβW. Hancock
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Article
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2007
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John Wiley and Sons
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English
β 429 KB
## Abstract Programmed cell deathβ1 (PDβ1, CD279) and its widely expressed, inducible ligand, PDβL1 (CD274), together dampen T cell activation, but whether they are essential for allograft tolerance is unknown. We show, using geneβdeficient mice and blocking mAbs in wildβtype mice, that costimulati