## Objectives: The purpose of this study is to identify and compare the presence and location of aquaporins in the fetal and adult larynx using immunohistochemical techniques. ## Methods: Immunohistochemical staining was performed on adult and fetal true vocal fold specimens. The presence and loc
Immunohistochemical identification of adult and fetal haemopoiesis in the spleen in lymphoma, leukaemia and myeloproliferative disease
✍ Scribed by J. C. E. Underwood; V. J. M. Dangerfield
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 773 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0022-3417
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Antisera to adult and fetal haemoglobins were used in the immunoperoxidase method to identify haemopoietic cells in spleens from patients with lymphoproliferative and myelopro‐liferative disorders. Splenic extramedullary haemopoiesis in adults often contains a major fetal component. Spleens infiltrated by Hodgkin's lymphoma are invariably negative, but other lymphomas, leukaemias and myeloproliferative diseases are commonly associated with splenic fetal haemopoiesis. Immunoperoxidase staining for haemoglobins is a useful way of determining the haemopoietic origin of round cell infiltrates in tissue sections.
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