✦ LIBER ✦

Immunohistochemical Analysis of Aquaporins in the Fetal and Adult Vocal Fold

✍ Scribed by Michael A. Goodier; Aimee P. Goodier; Alexandra S. Brown; John Schweinfurth

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 409 KB
Volume: 120
Category: Article
ISSN: 0023-852X
DOI: 10.1002/lary.21662

No coin nor oath required. For personal study only.

✦ Synopsis

Objectives:

The purpose of this study is to identify and compare the presence and location of aquaporins in the fetal and adult larynx using immunohistochemical techniques.

Methods:

Immunohistochemical staining was performed on adult and fetal true vocal fold specimens. The presence and location of aquaporins -1, -2 and -3 in the fetal specimens were then compared to the adult specimens.

Results:

Immunohistochemical analysis revealed a homogenous distribution of aquaporin -3 in the cell cytoplasm of adult lamina propria with a higher concentration in the superficial layer. Aquaporins -1 and -2 were not identified in either the adult specimens. No evidence of aquaporins were identified in the fetal lamina propria.

Conclusion:

Aquaporin -3 was found in the lamina propria of adult true vocal cord specimens with a higher concentration in the superficial layer. No evidence of Aquaporins -1, -2, or -3 was found in fetal specimens.

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