Immunohistochemical expression of p16INK4a is predictive of HR-HPV infection in cervical low-grade lesions
β Scribed by Benevolo, Maria; Mottolese, Marcella; Marandino, Ferdinando; Vocaturo, Giuseppe; Sindico, Roberto; Piperno, Giulia; Mariani, Luciano; Sperduti, Isabella; Canalini, Paola; Donnorso, Raffaele P
- Book ID
- 109888375
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 289 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0893-3952
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## Abstract ## BACKGROUND The primary goal of this study was to compare the clinical performance of an optimized and rigorously controlled immunocytochemical (ICC) assay for p16^INK4a^ to highβrisk (HR) human papillomavirus (HPV) detection by polymerase chain reaction (PCR) as diagnostic adjuncts
## Abstract Routine pathological examination cannot distinctively predict the clinical course of meningiomas because even histologically benign tumors may recur after gross total resection. Numerous efforts have been made for the evaluation of different immunohistochemical assays in meningioma prog