The AML14.3D10 human myeloid leukemic cell line expresses receptors for granulocytemacrophage colony stimulating factor (GM-CSF) and interleukin-5 (IL-5), but not IL-3. We have found that this cell line produces GM-CSF in amounts up to 113 pg/ml in culture supernatants. Deprivation of endogenous GM-
β¦ LIBER β¦
Immunohistochemical detection of GM-CSF, IL-4 and IL-5 in a murine model of allergic bronchopulmonary aspergillosis
β Scribed by H. W. CHU; J. M. WANG; M. BOUTET; L. P. BOULET; M. LAVIOLETTE
- Book ID
- 108686883
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 565 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0954-7894
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## Abstract ## Background Interleukinβ4 (ILβ4) plays a crucial role as an inflammatory mediator in allergic asthma via inducing Th2 inflammation and IgE synthesis. To develop an effective therapeutic agent which specifically inhibits production of ILβ4, antisense oligodeoxynucleotides (ASβODNs) ag