Immunohematology and Blood Banking II MD0846

✍ Scribed by US Army medical department

• Publisher: US Army medical department
• Year: 2006
• Tongue: English
• Leaves: 202
• Series: US Army medical course
• Edition: 100
• Category: Library

✦ Table of Contents

DEVELOPMENT
ADMINISTRATION
TABLE OF CONTENTS
INTRODUCTION
LESSON 1
Section I. THE IMMUNE RESPONSE AND THE INTERACTION OF ANTIGENS,ANTIBODIES, AND COMPLEMENT IN IMMUNOHEMATOLOGY
1-1. BACKGROUND
1-2. THE IMMUME RESPONSE
1-3. ANTIGENS
1-4. ANTIBODY SYNTHESIS
1-5. PRIMARY AND SECONDARY IMMUNE RESPONSES
1-6. IMMUNIZATION TO BLOOD-GROUP ANTIGENS
1-7. ANTIBODY STRUCTURE, FUNCTION, AND PROPERTIES
1-8. ANTIGEN-ANTIBODY REACTIONS IN BLOOD GROUP SEROLOGY
1-9. AGGLUTINATION
1-10. HEMOLYSIS
1-11. COMPLEMENT
1-12. THE CLASSIC COMPLEMENT PATHWAY
1-13. THE ALTERNATIVE COMPLEMENT PATHWAY
1-14. STABILITY OF COMPLEMENT WITH PARTICULAR REFERENCE TO THEDETECTION OF BLOOD-GROUP ANTIBODIES
Section II. THE ANTIGLOBULIN TEST
1-15. PRINCIPLES OF THE ANTIGLOBULIN TEST
1-16. DIRECT ANTIGLOBULIN TEST
1-17. INDIRECT ANT IGLOBULIN TEST
1-18. ROLE OF COMPLEMENT IN THE ANTIGLOBULIN REACTION
1-19. MECHANISMS FOR SENSITIZATION OF RED BLOOD CELLS BY COMPLEMENT
1-20. STANDARDIZATION OF ANTIGLOBULIN SERUMS
1-21. POLYSPECIFIC ANTIGLOBULIN REAGENTS
1-22. MONOSPECIFIC ANTIGLOBULIN SERUMS
1-23. FACTORS AFFECTING THE ANTIGLOBULIN TEST
1-24. SOURCES OF ERROR
Section III. RED BLOOD CELL ANTIBODIES
1-25. ALLOANTIBODIES
1-26. PROCEDURES
1-27. READING AND INTERPRETATION OF REACTIONS
1-28. REAGENT RED BLOOD CELLS
1-29. SERUM
1-30. CONTROLS
1-31. ANTIBODY DETECTION
1-32. ANTIBODY IDENTIFICATION
1-33. USE OF RED BLOOD CELL PANELS
1-34. ANTIGENIC FREQUENCY
1-35. INTERPRETATION OF COMMON PANEL RESULTS
1-36. ANTIBODIES NOT EASILY IDENTIFIED
1-37. USEFUL ADDITIONAL NOTES
1-38. COLD ANTIBODIES
1-39. TITRATION
1-40. ABSORPTION
1-41. ELUTION
Section IV. DETERMINATION OF COMPATIBILITY
1-42. DETERMINATION OF COMPATIBILITY
1-43. COLLECTION OF BLOOD FROM RECIPIENT
1-44. PRETRANSFUSION TESTING OF THE RECIPIENT
1-45. SELECTION OF BLOOD
1-46. MASSIVE TRANSFUSION
1-47. TECHNIQUES FOR CROSSMATCHING
1-48. INCOMPATIBLE CROSSMATCH
1-49. LABELING AND RELEASE OF CROSSMATCHED BLOOD
1-50. RETENTION AND STORAGE OF BLOOD SAMPLES
1-51. RELEASE OF BLOOD IN EMERGENCY SITUATIONS
1-52. CROSSMATCH IN PRESENCE OF PROLONGED CLOTTING TI
1-53. COMPATIBILITY TESTING AFTER INFUSION OF SYNTHETIC PLASMA EXPANDERS
EXERCISES
SOLUTIONS
LESSON 2
Section I. INVESTIGATION OF A POSITIVE DIRECT ANTIGLOBULIN TESTAND IMMUNE HEMOLYTIC ANEMIA
2-1. GENERAL
2-2. IMMUNE HEMOLYTIC ANEMIA
2-3. GENERAL SEROLOGIC INVESTIGATIONS
2-4. SPECIFICITY OF AUTOANTIBODY
2-5. COLD AGGLUTININ TITER. THERMAL AMPLITUDE, AND CONFIRMATIONOF ANTI-l(i) SPECIFICITY
2-6. ABO AND Rh GROUPING
2-7. AUTOIMMUNE HEMOLYTIC ANEMIA ASSOCIATED WITH WARM ANTIBODIES
2-8. AUTOIMMUNE HEMOLYTIC ANEMIA ASSOCIATED WITH COLD ANTIBODIES
2-9. DRUG-INDUCED "IN VIVO" RED BLOOD CELL SENSITIZATION
2-10. LABORATORY INVESTIGATION OP DRUG-RELATED PROBLEMS
2-11. DETECTION OF ANTIBODIES TO PENICILLIN AND CEPHALOTHIN
Section II. HEMOLYTIC DISEASE OF THE NEWBORN
2-12. BACKGROUND
2-13. CLASSIFICATION
2-14. MECHANISMS OF MATERNAL IMMUNIZATION
2-15. TRANSFER OF ANTIBODY TO THE FETUS
2-16. CLINICAL AND LABORATORY FEATURES OF HEMOLYTIC DISEASE
2-17. PRENATAL STUDIES
2-18. LABORATORY INVESTIGATION OF HEMOLYTIC DISEASE OF NEWBORNS DURING THE NEONATAL PERIOD
2-19. TREATMENT OF HEMOLYTIC DISEASE OF THE NEWBORN
2-20. RhO(D) IMMUNE GLOBULIN (HUMAN)-RhIG
2-21. MASSIVE FETOMATERNAL HEMORRHAGE
2-22. MATERNAL ALLOIMMUNIZATION TO PLATELETS, NEUTROPHILS, AND PROTEIN ALL O TYPES
EXERCISES
SOLUTIONS
LESSON 3
Section I. BLOOD TRANSFUSION PRACTICE
3-1. BACKGROUND
3-2. TRANSFUSION OF BLOOD PRODUCTS CONTAINING RED BLOOD CELLS
3-3. TRANSFUSION OF PLATELETS
3-4. BLOOD PRODUCTS USED TO REPLACE PLASMA COAGULATION FACTORS
3-5. PLASMA SUBSTITUTES
3-6. SPECIAL SITUATIONS INVOLVING TRANSFUSION
3-7. ADMINISTRATION OF BLOOD PRODUCTS
Section II. ADVERSE EFFECTS OF BLOOD TRANSFUSION
3-8. BACKGROUND
3-9. IMMEDIATE EFFECTS
3-10. DELAYED EFFECTS
3-11. RECORDS OF TRANSFUSION COMPLICATIONS
Section III. PREVENTION OF HEPATITIS
3-12. BACKGROUND
3-13. SELECTION OF DONORS
3-14. TESTING FOR HEPATITIS B SURFACE ANTIGEN AND HEPATITIS C IN BLOOD
3-15. RECIPIENT FOLLOW-UP FOR POST-TRANSFUSION HEPATITIS
3-16. HEPATITIS-IMPLICATED DONORS AND THOSE FOUND TO HAVE HEPATITIS B SURFACE ANTIGEN OR HEPATITIS C VIRUS
3-17. USE OF GAMMA GLOBULIN WITH TRANSFUSIONS
3-18. LABORATORY SAFETY
EXERCISES
SOLUTIONS
APPENDIX
BIBLIOGRAPHY