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Immunoglobulin V-gene somatic hypermutation in vitro


Book ID
103586336
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
96 KB
Volume
17
Category
Article
ISSN
0167-5699

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## A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro The functional immunoglobulin (Ig) genes of B lymphocytes undergo somatic mutations during immune responses. These mutations modify the antigen binding site of the immunoglobulins, thereby enhancin