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Immunoglobulin Heavy Chain Locus of the Rat: Striking Homology to Mouse Antibody Genes

✍ Scribed by Marianne Brüggemann, Jill Free, Austin Diamond, Jonathan Howard, Steve Cobbold and Herman Waldmann

Book ID
123633208
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
960 KB
Volume
83
Category
Article
ISSN
0027-8424

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We have previously used rat/mouse somatic cell hybrids to localize the rat c-myc gene to chromosome 7 (Siimegi et al. 1983) and the rat immunoglobulin kappa locus to chromosome 4 (Perlmann et al. 1985). We now report that by utilizing rat/mouse somatic cell hybrids, we have localized the rat immunog