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Immunogenicity of the recombinant ASP1r protein of A. caninum in a murine model

✍ Scribed by M.I. Giraldo; J.C. Castaño Osorio

Book ID
118451557
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
88 KB
Volume
14
Category
Article
ISSN
1201-9712

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Factor VIII (FVIII) is a multidomain protein that is deficient in hemophilia A, a clinically important bleeding disorder. Replacement therapy using recombinant human FVIII (rFVIII) is the main therapy. However, approximately 15-30% of patients develop inhibitory antibodies that neutralize rFVIII act