A hepatitis B vaccine produced in yeast by recombinant DNA technology was evaluated using 5-micrograms and 10-micrograms doses in a randomized trial lasting 7 months in 110 male armed forces recruits aged 17-19 years. Results were compared to those of an identical trial of a plasma-derived vaccine.
Immunogenicity and safety assessment of the Cuban recombinant hepatitis B vaccine in healthy adults
✍ Scribed by Zurina Cinza Estévez; Arístides Aguilar Betancourt; Verena Muzio González; Nelvis Figueroa Baile; Carmen Valenzuela Silva; Francisco Hernández Bernal; Eduardo Pentón Arias; Aurora Delhanty Fernández; Nelia Martin Olazábal; Amaurys del Río Martín; Lester Leal Batista; Gloria Véliz Ríos; Héctor Hernández Hernández; Aracelis Blanco Hernández; Evelyn Pérez Lugo; Joel de la Torre Cruz; Bertha L. Batista Marchec; Leovaldo Álvarez Falcón; Jannet Trujillo Brito; Darién Ortega León; Pedro López Saura
- Book ID
- 113491601
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 156 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1045-1056
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📜 SIMILAR VOLUMES
We tested the safety and long-term immunogenicity of two of the early investigative lots of a recombinant-yeast-derived hepatitis B vaccine in immunocompetent adults. Three 10-micrograms doses of recombinant hepatitis B vaccine (Merck Sharp & Dohme Research Laboratories, West Point, PA) were adminis