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Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. V. H-2 associativity of variant-specific antigens

✍ Scribed by Jacques van Snick; Janet Maryanski; Aline Van Pel; Giorgio Parmiani; Thierry Bonn


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
427 KB
Volume
12
Category
Article
ISSN
0014-2980

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Immunogenic variants obtained by mutagen
✍ J. L. Maryanski; M. Marchand; C. Uyttenhove; T. Boon πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 French βš– 504 KB

## Abstract After mutagenesis of mouse mastocytoma P815, it is possible to obtain variant (tum^βˆ’^) clones that are almost always rejected by syngeneic DBA/2 mice. Most tum^βˆ’^ clones express new variant‐specific antigens that can be detected by cytolytic T cells (CTL). Occasionally, mice injected wi